US 12,467,024 B2
Method of carrying out a bioreaction with multiple coupled vessels
Barbara Paldus, Woodside, CA (US); and Mark Selker, Los Altos Hills, CA (US)
Assigned to Finesse Solutions, Inc., Santa Clara, CA (US)
Filed by Finesse Solutions, Inc., Santa Clara, CA (US)
Filed on Nov. 14, 2023, as Appl. No. 18/509,131.
Application 17/677,517 is a division of application No. 15/427,613, filed on Feb. 8, 2017, granted, now 11,292,999, issued on Apr. 5, 2022.
Application 18/509,131 is a continuation of application No. 17/677,517, filed on Feb. 22, 2022, granted, now 11,859,161.
Claims priority of provisional application 62/381,283, filed on Aug. 30, 2016.
Prior Publication US 2024/0076594 A1, Mar. 7, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. C12M 1/00 (2006.01); C12M 1/02 (2006.01); C12M 1/06 (2006.01); C12M 1/12 (2006.01); C12M 1/26 (2006.01); C12M 1/34 (2006.01); C12M 3/00 (2006.01); C12M 3/06 (2006.01)
CPC C12M 23/02 (2013.01) [C12M 23/40 (2013.01); C12M 23/44 (2013.01); C12M 23/58 (2013.01); C12M 25/06 (2013.01); C12M 27/00 (2013.01); C12M 27/02 (2013.01); C12M 27/16 (2013.01); C12M 29/10 (2013.01); C12M 29/16 (2013.01); C12M 29/18 (2013.01); C12M 33/14 (2013.01); C12M 41/12 (2013.01); C12M 41/26 (2013.01); C12M 41/44 (2013.01)] 7 Claims
OG exemplary drawing
 
1. A method of carrying out a bioreaction in a multivessel bioreactor system, the method comprising:
coupling a master vessel to at least one satellite vessel in parallel by one or more separate fluidic paths configured for allowing bidirectional fluid flow between the master vessel and the at least one satellite vessel;
filling the master vessel with a first fluid, and filling the at least one satellite vessel with a second fluid;
detecting a first parameter for the first fluid in the master vessel with a master sensor coupled to the master vessel;
transmitting the first parameter from the master sensor to a control system in electronic communication with the master sensor; and
controlling with the control system a flow rate of fluid transfer through the one or more fluidic paths to maintain a substantially uniform value of the first parameter in the master vessel.