	US 12,466,883 B1
	Leptin compositions and methods of making and using the same to support weight loss and/or maintenance
James Michael Roberts, Seattle, WA (US); Mesfin Mulugeta Gewe, Bothell, WA (US); Uland Lau, Redmond, WA (US); Mark Heinnickel, Seattle, WA (US); Michael Dodds, Normandy Park, WA (US); David Bolick, Whitewater, CO (US); Nhi Yen Khuong, Kenmore, WA (US); Hannah Tabakh, Seattle, WA (US); Brian Finrow, Seattle, WA (US); and Jennifer Lynn Wierman, Ithaca, NY (US)
Assigned to LUMEN BIOSCIENCE, INC., Seattle, WA (US)
Filed by Lumen Bioscience, Inc., Seattle, WA (US)
Filed on May 13, 2025, as Appl. No. 19/207,094.
Claims priority of provisional application 63/646,354, filed on May 13, 2024.
Int. Cl. C07K 16/26 (2006.01); A61K 9/00 (2006.01); A61P 3/04 (2006.01); A61K 38/00 (2006.01)

CPC C07K 16/26 (2013.01) [A61K 9/0053 (2013.01); A61P 3/04 (2018.01); A61K 38/00 (2013.01)]

29 Claims

1. A recombinant leptin receptor agonist comprising an amino acid sequence having at least about 80% sequence identity with SEQ ID NO: 56.