US 12,466,817 B2
Pyridine derivative and application thereof
Yunfu Luo, Shanghai (CN); Yuyong Ba, Shanghai (CN); and Shuhui Chen, Shanghai (CN)
Assigned to Nicoya Therapeutics (Shanghai) Co., Ltd, Shanghai (CN)
Appl. No. 17/998,355
Filed by Nicoya Therapeutics (Shanghai) Co., Ltd, Shanghai (CN)
PCT Filed May 19, 2021, PCT No. PCT/CN2021/094677
§ 371(c)(1), (2) Date Nov. 9, 2022,
PCT Pub. No. WO2021/233349, PCT Pub. Date Nov. 25, 2021.
Claims priority of application No. 202010444113.6 (CN), filed on May 22, 2020.
Prior Publication US 2023/0183221 A1, Jun. 15, 2023
Int. Cl. C07D 405/14 (2006.01)
CPC C07D 405/14 (2013.01) 8 Claims
 
1. A compound represented by formula (I) or a pharmaceutically acceptable salt thereof,

OG Complex Work Unit Chemistry
wherein,
each of R1 is independently selected from halogen, OH, NH2, CN, C1-3 alkyl and C1-3 alkoxy, and the C1-3 alkyl and C1-3 alkoxy are optionally substituted by 1, 2 or 3 F;
m is selected from 0, 1 and 2;
ring A is selected from 5- to 6-membered heterocycloalkyl;
where the heterocycloalkyl contains 1, 2 or 3 heteroatoms or heteroatom groups independently selected from —O—, —NH—, —S—and N.