US 12,466,793 B2
Compounds for the treatment of SARS
Arun K. Ghosh, West Lafayette, IN (US); Monika Yadav, West Lafayette, IN (US); and Andrew Mesecar, West Lafayette, IN (US)
Assigned to Purdue Research Foundation, West Lafayette, IN (US)
Filed by Purdue Research Foundation, West Lafayette, IN (US)
Filed on Nov. 8, 2023, as Appl. No. 18/504,660.
Application 18/504,660 is a division of application No. 17/826,061, filed on May 26, 2022, granted, now 11,834,408.
Claims priority of provisional application 63/194,638, filed on May 28, 2021.
Prior Publication US 2024/0116865 A1, Apr. 11, 2024
Int. Cl. C07D 207/26 (2006.01); C07D 227/087 (2006.01)
CPC C07D 207/26 (2013.01) [C07D 227/087 (2013.01)] 15 Claims
 
1. A compound of the formula (I):

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt thereof, wherein:
R1 is

OG Complex Work Unit Chemistry
R2 is alkyl, aryl, substituted aryl;
R3 is:

OG Complex Work Unit Chemistry
wherein m is 1 or 2;
R4 is H, alkyl or alkenyl; and
Ra is H or alkyl,
or a pharmaceutically acceptable salt thereof.