US 12,465,892 B2
Method for evaluating covering state of silicone compound
Takeshi Sato, Kanagawa (JP); and Renjo Takama, Kanagawa (JP)
Assigned to TERUMO KABUSHIKI KAISHA, Tokyo (JP)
Filed by TERUMO KABUSHIKI KAISHA, Tokyo (JP)
Filed on Aug. 29, 2023, as Appl. No. 18/239,352.
Application 18/239,352 is a continuation of application No. PCT/JP2022/006839, filed on Feb. 21, 2022.
Claims priority of application No. 2021-034251 (JP), filed on Mar. 4, 2021.
Prior Publication US 2023/0398501 A1, Dec. 14, 2023
Int. Cl. B01D 65/10 (2006.01); B01D 63/02 (2006.01)
CPC B01D 65/102 (2013.01) [B01D 63/02 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A method for evaluating a covering state of a silicone compound on a hollow fiber membrane for treating blood in an oxygenator, comprising the steps of:
dissolving a silicone compound and a dyeing agent in an organic solvent to prepare a coating solution;
causing the coating solution to pass through an inner surface of a hollow fiber membrane to form a coating layer containing the silicone compound and/or a crosslinked product of the silicone compound and the dyeing agent on the inner surface; and
evaluating a covering state of the silicone compound/the crosslinked product by observing a dyed state of a hollow fiber membrane end surface on a coating solution passing start side and a dyed state of a hollow fiber membrane end surface on a coating solution passing end side of the hollow fiber membrane on which the coating layer is formed.