US 12,465,761 B2
Electrical stimulation system for the treatment of gastrointestinal disorders
Paul V. Goode, Round Rock, TX (US); and Virender K. Sharma, Paradise Valley, AZ (US)
Filed by EndoStim, Inc., Dallas, TX (US)
Filed on Feb. 6, 2019, as Appl. No. 16/269,503.
Claims priority of provisional application 62/627,014, filed on Feb. 6, 2018.
Prior Publication US 2019/0240484 A1, Aug. 8, 2019
Int. Cl. A61N 1/36 (2006.01); A61N 1/05 (2006.01); A61N 1/08 (2006.01); A61N 1/18 (2006.01); A61N 1/372 (2006.01); A61N 1/375 (2006.01)
CPC A61N 1/36007 (2013.01) [A61N 1/05 (2013.01); A61N 1/0504 (2013.01); A61N 1/0509 (2013.01); A61N 1/0517 (2013.01); A61N 1/18 (2013.01); A61N 1/36 (2013.01); A61N 1/3606 (2013.01); A61N 1/36157 (2013.01); A61N 1/36171 (2013.01); A61N 1/36175 (2013.01); A61N 1/08 (2013.01); A61N 1/36071 (2013.01); A61N 1/36139 (2013.01); A61N 1/37247 (2013.01); A61N 1/37288 (2013.01); A61N 1/3752 (2013.01)] 12 Claims
OG exemplary drawing
 
1. A method for increasing an end expiratory pressure of a patient's lower esophageal sphincter (LES) by implanting a stimulation system in the patient, wherein the stimulation system comprises one or more electrodes and a stimulator module comprising a pulse generator and a power source, and wherein the stimulator module is in electrical communication with the one or more electrodes through one or more leads, the method comprising:
implanting the one or more electrodes proximate the LES of the patient;
forming a subcutaneous pocket in the patient;
placing the stimulator module in the subcutaneous pocket, wherein the one or more leads are connected to the stimulator module located in the subcutaneous pocket, and wherein the one or more leads are connected to the one or more electrodes; and
causing the end expiratory pressure of the patient's LES to increase by activating the stimulator module to generate a plurality of electrical pulses, wherein the electrical pulses are defined by parameters comprising a frequency in a range of 1 Hz to 300 Hz, a pulse amplitude in a range of 0.5 mA to 30 mA, a pulse width in a range of around 30 usec to 5 msec, and a session duration in a range of 1 minute to 1 day, and wherein said parameters are adapted to increase the end expiratory pressure of the patient's LES.