| CPC A61N 1/0502 (2013.01) [A61N 1/328 (2013.01); A61N 1/36017 (2013.01); A61N 1/36031 (2017.08); A61N 1/44 (2013.01); A61N 1/0476 (2013.01); A61N 2001/083 (2013.01)] | 23 Claims |

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1. A system comprising:
an applicator comprising
an electrode assembly comprising
a substrate, and
a needle array comprising a plurality of needles, the needle array extending from the substrate, the plurality of needles arranged in a pattern; and
a handpiece coupled to the electrode assembly; and
a control system in electrical communication with the plurality of needles;
wherein the control system is configured to detect a location of an enlarged sebaceous gland in response to an impedance measured using two or more needles of the plurality of needles, wherein the control system is configured to energize one or more of the plurality of needles to treat the enlarged sebaceous gland, wherein normally sized sebaceous glands are spared from targeted energy exposure.
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