US 12,465,675 B2
Method and apparatus for identifying disruption of a fluid connection between an extracorporeal circuit and a patient circulatory system
Nikolai M. Krivitski, Ithaca, NY (US); Gregory Galyanov, Ithaca, NY (US); and Cornelis J. Drost, Ithaca, NY (US)
Assigned to Transonic Systems Inc., Ithaca, NY (US)
Filed by Transonic Systems Inc., Ithaca, NY (US)
Filed on Apr. 5, 2022, as Appl. No. 17/713,940.
Application 17/713,940 is a continuation in part of application No. 17/387,391, filed on Jul. 28, 2021.
Prior Publication US 2023/0036473 A1, Feb. 2, 2023
Int. Cl. A61M 1/36 (2006.01)
CPC A61M 1/3656 (2014.02) [A61M 1/3639 (2013.01); A61M 2205/15 (2013.01); A61M 2205/18 (2013.01); A61M 2205/3331 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A system for detecting a disruption of a fluid connection between an extracorporeal circuit and a patient circulatory system, the system comprising
(a) an extracorporeal circuit extending from a patient circulatory system through a patient blood withdrawal site to an extracorporeal blood treatment device and returning to the patient circulatory system through a patient blood delivery site, the extracorporeal circuit including a blood withdrawal line extending from a patient blood withdrawal site to the a blood treatment device, a blood delivery line extending from the blood treatment device to the a patient blood delivery site, and a pump configured to pump blood through at least a portion of the extracorporeal circuit;
(b) a flow sensor configured to obtain flow rate data of a flow in a portion of the extracorporeal circuit; and
(c) a controller in communication with the flow sensor, the controller configured to:
i) identify an inharmonic change in the flow rate data; and
ii) send a control signal if a disruption of the fluid connection between the extracorporeal circuit and the patient circulatory system is detected based at least partly on the identified inharmonic change in the flow rate data, the control signal configured to instruct the system to perform at least one of activating an alarm unit or stopping the pump.