US 12,465,650 B2
Methods and compositions for targeting cancer cells in metastases
Mikhail Kolonin, Houston, TX (US); Alexes Daquinag, Houston, TX (US); and Shraddha Subramanian, Houston, TX (US)
Assigned to THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US)
Filed by THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US)
Filed on Aug. 12, 2022, as Appl. No. 17/819,474.
Claims priority of provisional application 63/232,435, filed on Aug. 12, 2021.
Prior Publication US 2023/0056203 A1, Feb. 23, 2023
Int. Cl. A61K 47/64 (2017.01); A61P 35/04 (2006.01); C07K 14/47 (2006.01)
CPC A61K 47/64 (2017.08) [A61P 35/04 (2018.01); C07K 14/4702 (2013.01)] 17 Claims
 
1. A targeting polypeptide comprising the amino acid sequence selected from the group consisting of Breast Lung Metastasis-Homing Peptide (BLMP) 1-6 (SEQ ID NOs: 1-6), and wherein said targeting polypeptide binds to solid tumor cells, wherein the targeting polypeptide is less than 100 amino acids in length.