US 12,465,584 B2
Agent for elevating nitric oxide concentration
Masahiko Morita, Tokyo (JP); and Ayako Kamimura, Tokyo (JP)
Assigned to KYOWA HAKKO BIO CO., LTD., Tokyo (JP)
Filed by KYOWA HAKKO BIO CO., LTD., Tokyo (JP)
Filed on Apr. 11, 2023, as Appl. No. 18/298,825.
Application 18/298,825 is a division of application No. 14/762,108, granted, now 11,654,125, previously published as PCT/JP2014/051102, filed on Jan. 21, 2014.
Claims priority of application No. 2013-008239 (JP), filed on Jan. 21, 2013.
Prior Publication US 2023/0263761 A1, Aug. 24, 2023
Int. Cl. C12P 21/02 (2006.01); A61K 31/198 (2006.01); A61K 38/06 (2006.01); A61P 3/00 (2006.01); A61P 3/02 (2006.01); A61P 3/04 (2006.01); A61P 3/06 (2006.01); A61P 7/10 (2006.01); A61P 9/00 (2006.01); A61P 9/10 (2006.01); A61P 9/12 (2006.01); A61P 11/00 (2006.01); A61P 13/12 (2006.01); A61P 15/10 (2006.01); A61P 17/00 (2006.01); A61P 21/02 (2006.01); A61P 25/28 (2006.01); A61P 27/02 (2006.01); A61P 43/00 (2006.01)
CPC A61K 31/198 (2013.01) [A61K 38/063 (2013.01)] 4 Claims
 
1. A method for elevating nitric oxide (NO) concentration comprising orally administering glutathione or a salt thereof at a dose of 10 mg to 10 g per day to elevate the NO concentration of a subject who desires improvement in exercise performance,
wherein the glutathione or a salt thereof is orally administered as a tablet, a powder, a granule, a pill, an infusion decoction, a capsule, a drink with glutathione dissolved therein, a drink with a salt of glutathione dissolved therein, a solution, an elixir, an extract, a tincture, or a fluid extract, and
wherein the elevated NO concentration causes exercise performance improvement in the subject.