US 12,465,581 B2
Compositions for improving gut health and/or milk production in ruminants, uses and methods thereof
Jean Fontaine, Saint-Hyacinthe (CA); Jean-Daniel Bunod, Saint-Hyacinthe (CA); Ousama Alzahal, Saint-Hyacinthe (CA); Abdallah Zankar, Saint-Hyacinthe (CA); Essi Evans, Saint-Hyacinthe (CA); Elizabeth Santin, Saint-Hyacinthe (CA); Ludovic Lahaye, Saint-Hyacinthe (CA); and Emilie Fontaine, Saint-Hyacinthe (CA)
Assigned to JEFO NUTRITION INC., Saint-Hyacinthe (CA)
Appl. No. 18/834,538
Filed by JEFO NUTRITION INC., Saint-Hyacinthe (CA)
PCT Filed Feb. 2, 2023, PCT No. PCT/CA2023/050140
§ 371(c)(1), (2) Date Jul. 30, 2024,
PCT Pub. No. WO2023/147665, PCT Pub. Date Aug. 10, 2023.
Claims priority of provisional application 63/305,972, filed on Feb. 2, 2022.
Prior Publication US 2025/0108025 A1, Apr. 3, 2025
Int. Cl. A61K 35/74 (2015.01); A61K 31/05 (2006.01); A61K 31/085 (2006.01); A61K 31/11 (2006.01); A61K 31/19 (2006.01); A61K 31/194 (2006.01); A61K 31/7048 (2006.01); A61K 35/742 (2015.01); A61K 36/185 (2006.01); A61K 47/02 (2006.01); A61K 47/12 (2006.01); A61K 47/36 (2006.01); A61K 47/44 (2017.01); A61K 47/46 (2006.01); A61K 35/00 (2006.01)
CPC A61K 31/194 (2013.01) [A61K 31/05 (2013.01); A61K 31/085 (2013.01); A61K 31/11 (2013.01); A61K 31/19 (2013.01); A61K 31/7048 (2013.01); A61K 35/742 (2013.01); A61K 36/185 (2013.01); A61K 47/02 (2013.01); A61K 47/12 (2013.01); A61K 47/36 (2013.01); A61K 47/44 (2013.01); A61K 47/46 (2013.01); A61K 2035/115 (2013.01)] 23 Claims
OG exemplary drawing
 
1. A mixture, comprising:
(a) a first composition comprising organic acids comprising fumaric acid, sorbic acid, citric acid, and malic acid, or salts thereof, essential oils comprising thymol, eugenol and vanillin, and optionally a first controlled release matrix;
(b) a second composition comprising bacterial fermentation products comprising a Bacillus amyloliquefaciens fermentation extract, a Bacillus subtilis fermentation extract and a Streptomyces sp. fermentation extract, and optionally a second controlled release matrix; and
(c) a third composition comprising a plant extract comprising a saponin, and
(d) optionally a third controlled release matrix.