	US 12,465,567 B2
	Enhanced antibiotic and drug delivery for aqueous topical applications for human and veterinary uses
Christopher Ayo Otiko, Tarzana, CA (US); and David R. Pozek, Dearborn, MI (US)
Assigned to Christopher Ayo Otiko, Tarzana, CA (US)
Filed by Christopher Ayo Otiko, Tarzana, CA (US)
Filed on Jul. 25, 2019, as Appl. No. 16/522,259.
Claims priority of provisional application 62/757,891, filed on Nov. 9, 2018.
Prior Publication US 2020/0146983 A1, May 14, 2020
Int. Cl. A61K 9/06 (2006.01); A61K 31/35 (2006.01); A61K 31/39 (2006.01); A61K 31/59 (2006.01); A61K 31/65 (2006.01)

CPC A61K 9/06 (2013.01) [A61K 31/59 (2013.01); A61K 31/65 (2013.01)]

3 Claims

1. An antibiotic ointment for wound care comprising:

3% tetracycline HCl as an active antibiotic agent;

15% dimethyl sulfoxide operating as a tissue penetrating solvent;

oleic acid as a tissue penetrating agent;

85% dipropylene glycol as a tissue penetrating diluent; and

a stabilizer comprising 1% ascorbic acid for maintaining the ointment, which also functions as a stabilizer for maintaining chemical stability and resistance to degradation;

wherein the oleic acid is combined with the dimethyl sulfoxide and the tetracycline HCl, thereby releasing, over time, the dimethyl sulfoxide which operates to further penetrate the tissue and delivering the tetracycline HCl to the wound.