US 12,465,481 B2
Light adjustable intraocular lens with a modulable absorption front protection layer
Ilya Goldshleger, Ladera Ranch, CA (US); John Kondis, Irvine, CA (US); and Ritu Shrestha, Santa Ana, CA (US)
Assigned to RxSight, Inc., Aliso Viejo, CA (US)
Filed by RxSight, Inc., Aliso Viejo, CA (US)
Filed on May 16, 2024, as Appl. No. 18/666,508.
Application 18/666,508 is a continuation of application No. 17/583,329, filed on Jan. 25, 2022, granted, now 12,102,524.
Application 17/583,329 is a continuation of application No. 16/658,142, filed on Oct. 20, 2019, granted, now 11,266,495, issued on Mar. 8, 2022.
Prior Publication US 2024/0299158 A1, Sep. 12, 2024
Int. Cl. A61F 2/16 (2006.01)
CPC A61F 2/1624 (2013.01) [A61F 2/1627 (2013.01); A61F 2/1635 (2013.01); A61F 2/1659 (2013.01); A61F 2002/1683 (2013.01); A61F 2002/16965 (2015.04); A61F 2210/0085 (2013.01); A61F 2250/0001 (2013.01)] 2 Claims
OG exemplary drawing
 
1. A method of adjusting an optical property of a modulable absorption light adjustable intraocular lens (IOL) for implantation into an eye, the method comprising:
reducing an absorption of a modulable absorption compound of a modulable absorption front protection layer of the intraocular lens by applying a high-to-low modulating stimulus for transforming the modulable absorption compound from a high-absorption conformation to a low-absorption conformation, the intraocular lens having been previously implanted into an eye;
changing an optical property of a light adjustable lens of the intraocular lens by applying an adjusting irradiation; and
transforming the modulable absorption compound from a low-absorption conformation to a high-absorption conformation by applying a low-to-high modulating stimulus,
wherein the light adjustable lens comprises a photo-modifiable material that includes:
a polymer host matrix;
at least one of monomers and macromers, capable of photo-induced polymerization;
a photoinitiator; and
dispersed ultraviolet absorbers,
wherein the modulable absorption front protection layer includes one of:
a layer in the frontal region of the light adjustable lens;
a layer attached onto the frontal region of the light adjustable lens; and
a layer deposited onto the frontal region of the light adjustable lens.