US 12,465,320 B1
Wearable device for non-invasive monitoring of intracranial pressure through ophthalmic biomarkers
Viksit Kumar, Ashburn, VA (US); Khurram Hassan-Shafique, Aldie, VA (US); and Zeeshan Rasheed, Great Falls, VA (US)
Assigned to Novateur Research Solutions, Ashburn, VA (US)
Filed by Novateur Research Solutions, Ashburn, VA (US)
Filed on Apr. 21, 2025, as Appl. No. 19/184,843.
Int. Cl. A61B 8/08 (2006.01); A61B 8/00 (2006.01); A61B 8/10 (2006.01); G06T 7/00 (2017.01); G06T 7/62 (2017.01); G16H 10/60 (2018.01)
CPC A61B 8/08 (2013.01) [A61B 8/10 (2013.01); A61B 8/4227 (2013.01); A61B 8/4281 (2013.01); A61B 8/4461 (2013.01); A61B 8/463 (2013.01); A61B 8/54 (2013.01); A61B 8/56 (2013.01); G06T 7/0012 (2013.01); G06T 7/62 (2017.01); G16H 10/60 (2018.01); G06T 2207/10132 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/30041 (2013.01); G06T 2207/30168 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A wearable device for non-invasive monitoring of intracranial pressure (ICP), comprising:
a wearable structure configured to be secured to a head of a user;
at least one ultrasound transducer integrated within the wearable structure and configured to be positioned to align with an eye of the user when worn;
a motorized control mechanism with six degrees of freedom that is configured to dynamically adjust a position and angulation of the at least one ultrasound transducer;
a fluid management system that is configured to maintain an acoustic coupling between the at least one ultrasound transducer and the eye of the user;
an integrated air vent system that is configured to regulate pressure, prevent condensation, and maintain imaging quality within the wearable structure;
a processor coupled to the ultrasound transducer, wherein the processor is configured to:
employ a reinforcement learning-based control system for optimizing transducer placement;
acquire ultrasound images of an optic nerve sheath;
analyze the ultrasound images to measure an optic nerve sheath diameter (ONSD); and
determine a likelihood of elevated intracranial pressure based on the measured ONSD;
a hinged lens mechanism that is configured to allow selective opening and closing for temporary vision access without removing the device from the user;
a wide-angle camera that is configured to provide real-time anatomical visualization to assist in transducer positioning; and
a graphical user interface that is configured to display diagnostic information based on the determined likelihood of elevated intracranial pressure.