US 12,137,514 B2
Linear accelerator for generating high X-ray doses
Ronald Agustsson, Venice, CA (US); Salime Boucher, Santa Monica, CA (US); and Sergey Kutsaev, Santa Monica, CA (US)
Assigned to RadiaBeam Technologies, LLC, Santa Monica, CA (US)
Appl. No. 17/754,764
Filed by RadiaBeam Technologies, LLC, Santa Monica, CA (US)
PCT Filed Dec. 2, 2020, PCT No. PCT/US2020/062835
§ 371(c)(1), (2) Date Apr. 11, 2022,
PCT Pub. No. WO2021/113323, PCT Pub. Date Jun. 10, 2021.
Claims priority of provisional application 62/944,574, filed on Dec. 6, 2019.
Prior Publication US 2024/0090112 A1, Mar. 14, 2024
Int. Cl. H05H 7/04 (2006.01); H05H 9/04 (2006.01)
CPC H05H 7/04 (2013.01) [H05H 9/048 (2013.01); H05H 2007/048 (2013.01); H05H 2277/11 (2013.01)] 24 Claims
OG exemplary drawing
 
1. An X-ray generation system configured to generate an X-ray beam configured to be delivered to a patient undergoing radiation therapy, the X-ray generation system comprising a linear accelerator system configured to generate an electron beam having an electron beam energy in a range of 6 MeV to 25 MeV and a peak electron beam current during a treatment delivery window in a range of 0.2 A to 10 A, the electron beam configured to impinge a target configured to respond to the incident electron beam by emitting an X-ray beam configured to deliver an X-ray dose rate to the patient in a range of 40 Gy/s to 1000 Gy/s within the treatment delivery window.
 
14. An X-ray generation system configured to generate an X-ray beam configured to be delivered to a patient undergoing radiation therapy, the X-ray generation system comprising:
a controllably rotatable gantry having a rotation axis about which a rotatable portion of the gantry is configured to rotate, the rotation axis configured to extend through the patient undergoing radiation therapy;
a linac configured to generate an electron beam having an electron beam energy in a range of 6 MeV to 25 MeV and a peak electron beam current during a treatment delivery window in a range of 0.2 A to 10 A;
a target mounted in or on the rotatable portion of the gantry and configured to generate an X-ray beam in response to being irradiated by the electron beam, the X-ray beam configured to irradiate the patient with an X-ray dose rate in a range of 40 Gy/s to 1000 Gy/s within the treatment delivery window; and
an electron optics sub-system comprising at least one magnet mounted in or on the rotatable portion of the gantry, the electron optics sub-system configured to direct the electron beam from propagating in a first direction from the linac to propagating in a second direction towards the target.
 
22. An X-ray generation system configured to generate an X-ray beam configured to be delivered to a patient undergoing radiation therapy, the X-ray generation system comprising:
a gantry configured to extend at least partially around the patient undergoing radiation therapy;
a linac configured to generate an electron beam;
a plurality of targets mounted in or on the gantry, each target of the plurality of targets configured to generate an X-ray beam in response to being irradiated by the electron beam, the X-ray beams from the plurality of targets configured to irradiate the patient; and
an electron optics sub-system mounted in or on the gantry, the electron optics sub-system comprising:
at least one controllably switchable magnet configured to receive the electron beam propagating in a first direction from the linac and to deflect the electron beam into a selected one of two or more second directions; and
two or more pluralities of magnets, each plurality of magnets of the two or more pluralities of magnets configured to receive the electron beam propagating in one of the two or more second directions from the at least one controllably switchable magnet and to direct the electron beam to propagate in a corresponding third direction towards a target of the plurality of targets.