US 12,135,324 B2
Immunochromatographic assay device
Xuan Meng, Guangzhou (CN); Jiaming Du, Guangzhou (CN); and Xirong Huang, Guangzhou (CN)
Assigned to GUANGZHOU WONDFO BIOTECH CO., LTD., Guangzhou (CN)
Appl. No. 17/422,004
Filed by GUANGZHOU WONDFO BIOTECH CO., LTD., Guangzhou (CN)
PCT Filed Jul. 31, 2019, PCT No. PCT/CN2019/098730
§ 371(c)(1), (2) Date Jul. 9, 2021,
PCT Pub. No. WO2020/143220, PCT Pub. Date Jul. 16, 2020.
Claims priority of application No. 201910026644.0 (CN), filed on Jan. 11, 2019.
Prior Publication US 2022/0099668 A1, Mar. 31, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. G01N 33/543 (2006.01); B01L 3/00 (2006.01)
CPC G01N 33/54389 (2021.08) [B01L 3/5023 (2013.01); B01L 2300/069 (2013.01); B01L 2300/08 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0825 (2013.01); B01L 2300/0838 (2013.01); B01L 2300/0887 (2013.01)] 8 Claims
OG exemplary drawing
 
1. An immunochromatographic assay device comprising a cover plate, immunochromatographic assay components, and a sample loading baseplate;
wherein the cover plate mates with the sample loading baseplate to define a testing cavity; the sample loading base plate has a sample loading portion which is located in the testing cavity; the cover plate is provided with a sample adding hole corresponding to the sample loading portion, the sample loading portion is configured to receive a sample solution and is provided with a plurality of adjacent mounting positions, and the adjacent mounting positions are arranged at intervals; the immunochromatographic assay components are a plurality of immunochromatographic assay components mounted on the plurality of mounting positions respectively; the sample loading portion mates with the cover plate to define a wetting zone at least in the part close to the mounting positions, and the wetting zone has such a height that when the sample solution arrives at the wetting zone, the sample solution is capable of flowing along a surface of the sample loading portion toward the plurality of immunochromatographic assay components under the propulsion of capillary action;
wherein the sample loading portion has a multi-step structure, the multi-step structure has a height increasing stepwise along a direction moving away from the sample adding hole, and each of the mounting positions is a long strip-shaped groove-shaped structure extending along a top surface of a highest step, configured to embed and mount one of the plurality of immunochromatographic assay components, wherein each immunochromatographic assay component comprises a long strip-shaped immunochromatographic test paper; the highest step is directly connected to the strip-shaped immunochromatographic test paper, and a length of a top surface of a lowest step along a width direction of the immunochromatographic assay device gradually increases as the lowest step approaches a higher step connected thereto.