US 12,135,282 B2
Method of imaging a sample material
Vincent Patrick Wallace, Crawley (AU); Anthony James Fitzgerald, Crawley (AU); and Adam Philip Gibson, London (GB)
Assigned to The University of Western Australia, Crawley (AU)
Appl. No. 17/637,647
Filed by The University of Western Australia, Crawley (AU)
PCT Filed Aug. 28, 2020, PCT No. PCT/AU2020/050913
§ 371(c)(1), (2) Date Feb. 23, 2022,
PCT Pub. No. WO2021/035312, PCT Pub. Date Mar. 4, 2021.
Claims priority of application No. 2019903145 (AU), filed on Aug. 28, 2019; and application No. 2020900447 (AU), filed on Feb. 17, 2020.
Prior Publication US 2022/0276161 A1, Sep. 1, 2022
Int. Cl. G01N 21/3581 (2014.01); G01B 11/06 (2006.01); G01N 21/31 (2006.01); G01N 21/41 (2006.01); A61B 5/0507 (2021.01)
CPC G01N 21/3581 (2013.01) [G01B 11/06 (2013.01); G01N 21/3151 (2013.01); G01N 21/41 (2013.01); A61B 5/0507 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A method of analyzing an area of interest of a sample material, the method comprising the steps of:
directing a first radiation to a first area of interest, the first radiation having frequencies within a terahertz frequency range;
receiving a first signal THz1 being a quantity related to radiation received from the first area of interest in response to directing the first radiation to the first area of interest, the first signal THz1 being dependent on a first property and on a second property of the first area of interest;
directing a second radiation to the first area of interest, the second radiation having frequencies within a frequency range that is different to that of the first radiation;
receiving a second signal IR1 being a quantity related to radiation received from the first area interest in response to directing the second radiation to the first area of interest, the second signal IR1 being dependent on the second property of the first area of interest;
scaling or co-registering times of flight associated with the first signal THz1 and the second signal IR1 such that the scaled co-registered time of flight corresponds to matching depths within the sample material; and
analyzing the first signal THz1 using the second signal IR1 to identify first information indicative of the first property of the first area of interest.