US 12,135,274 B2
Outlet fittings for reducing bubbles at the interface with a flow cell, and flow cytometers and methods using the same
Kyle Dembski, Scotts Valley, CA (US)
Assigned to Becton, Dickinson and Company, Franklin Lakes, NJ (US)
Filed by Becton, Dickinson and Company, Franklin Lakes, NJ (US)
Filed on Jul. 18, 2022, as Appl. No. 17/867,394.
Claims priority of provisional application 63/231,403, filed on Aug. 10, 2021.
Prior Publication US 2023/0046207 A1, Feb. 16, 2023
Int. Cl. G01N 15/1434 (2024.01); G01N 15/10 (2024.01); G01N 15/1404 (2024.01); G01N 33/487 (2006.01)
CPC G01N 15/1434 (2013.01) [G01N 15/1404 (2013.01); G01N 33/487 (2013.01); G01N 2015/1006 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A flow cytometer comprising:
a flow cell comprising a flow channel for transporting particles in a flow stream therethrough from an inlet at a proximal end to an outlet at a distal end;
a light source for irradiating the flow stream at an interrogation point;
a detector configured to receive particle-modulated light from the flow stream; and
an outlet fitting comprised of an elongate structure and an opening at a proximal end of the elongate structure for receiving the flow stream from the distal end of the flow cell, wherein the outlet fitting is configured to reduce the formation of bubbles at the interface between the outlet fitting and the flow cell, and operably couple to a waste line at a distal end of the elongate structure.