US 12,134,779 B2
Hydrogel particles as feeder cells and as synthetic antigen presenting cells
Anh Tuan Nguyen, San Francisco, CA (US); Jeffrey Kim, Berkeley, CA (US); Keunho Ahn, Pleasanton, CA (US); and Daixuan Zhang, Fremont, CA (US)
Assigned to Slingshot Biosciences, Inc., Emeryville, CA (US)
Filed by Slingshot Biosciences, Inc., Emeryville, CA (US)
Filed on Nov. 1, 2023, as Appl. No. 18/386,107.
Application 18/386,107 is a continuation of application No. PCT/US2022/048283, filed on Oct. 28, 2022.
Claims priority of provisional application 63/320,016, filed on Mar. 15, 2022.
Claims priority of provisional application 63/320,009, filed on Mar. 15, 2022.
Claims priority of provisional application 63/274,316, filed on Nov. 1, 2021.
Claims priority of provisional application 63/273,741, filed on Oct. 29, 2021.
Prior Publication US 2024/0060038 A1, Feb. 22, 2024
Int. Cl. C12N 5/00 (2006.01); C12M 1/42 (2006.01)
CPC C12N 5/0018 (2013.01) [C12M 35/06 (2013.01); C12N 2500/50 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A magnetic capture hydrogel particle, comprising:
a) a hydrogel matrix, said hydrogel matrix comprising a magnetic material embedded and/or encapsulated therein, such that the hydrogel particle is capable of being attracted to or repelled by a magnetic field; and
b) a ligand capable of binding the hydrogel matrix to a capture target molecule,
wherein the magnetic capture hydrogel particle is spherical and has a diameter of between about 2 μm and about 5 μm.