US 12,134,664 B2
Muramyl peptide derivatives
Krishna Murthy Ella, Hyderabad (IN); Ganneru Brunda, Hyderabad (IN); Halmuthur Mahabalarao Sampath Kumar, Hyderabad (IN); and Paturu Rama Subba Reddy, Hyderabad (IN)
Assigned to Bharat Biotech International LTD., Hyderabad (IN); and Council of Scientific and Industrial Research, Hyderabad (IN)
Filed by Bharat Biotech International Limited, Hyderabad (IN); and Council of Scientific and Industrial Research, New Delhi (IN)
Filed on May 24, 2021, as Appl. No. 17/328,078.
Application 17/328,078 is a continuation in part of application No. 17/092,711, filed on Nov. 9, 2020, abandoned.
Application 17/092,711 is a continuation of application No. 16/060,093, granted, now 10,927,147, issued on Feb. 23, 2021, previously published as PCT/IN2016/050436, filed on Dec. 6, 2016.
Claims priority of application No. 6436/CHE/2015 (IN), filed on Dec. 10, 2015.
Prior Publication US 2022/0056080 A1, Feb. 24, 2022
Int. Cl. C07K 9/00 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61K 39/12 (2006.01); A61P 31/04 (2006.01); A61P 31/12 (2006.01); A61P 33/00 (2006.01)
CPC C07K 9/005 (2013.01) [A61K 39/12 (2013.01); A61K 38/00 (2013.01); A61K 2039/5555 (2013.01); A61K 2039/572 (2013.01); A61K 2039/575 (2013.01); A61P 31/04 (2018.01); A61P 31/12 (2018.01); A61P 33/00 (2018.01); C12N 2710/00034 (2013.01)] 20 Claims
 
1. A compound comprising a muramyl dipeptide of the formula:

OG Complex Work Unit Chemistry
wherein R is a linear alkyl, aryl, substituted aryl or alkoxy alkyl with 4 or more carbons.