US 12,134,646 B2
Anti-C-KIT antibody
Sang Gyu Park, Yongin-si (KR); and Jin-Ock Kim, Jeungpyeong-gun (KR)
Assigned to NOVELTY NOBILITY INC., Suwon-si (KR)
Appl. No. 17/284,672
Filed by NOVELTY NOBILITY INC., Suwon-si (KR)
PCT Filed Oct. 10, 2019, PCT No. PCT/KR2019/013310
§ 371(c)(1), (2) Date Apr. 12, 2021,
PCT Pub. No. WO2020/076105, PCT Pub. Date Apr. 16, 2020.
Claims priority of application No. 10-2018-0120233 (KR), filed on Oct. 10, 2018.
Prior Publication US 2021/0355212 A1, Nov. 18, 2021
Int. Cl. C07K 16/28 (2006.01); A61K 39/00 (2006.01); A61P 9/00 (2006.01)
CPC C07K 16/2803 (2013.01) [A61P 9/00 (2018.01); A61K 2039/505 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01)] 11 Claims
 
1. An anti-C-KIT antibody or antibody fragment thereof, specifically binding to domain II of C-KIT, wherein the anti-C-KIT antibody or antibody fragment thereof comprises a light chain variable region comprising a light chain CDR1 of SEQ ID NO: 1, a light chain CDR2 of SEQ ID NO: 2, and a light chain CDR3 of SEQ ID NO: 3; and a heavy chain variable region comprising a heavy chain CDR1 of SEQ ID NO: 4, a heavy chain CDR2 of SEQ ID NO: 5, and a heavy chain CDR3 of SEQ ID NO: 6.