US 12,134,638 B2
SIRPalpha-4-1BBL variant fusion protein and methods of use thereof
Iris Pecker, Rishon LeZion (IL); and Itai Bloch, Moshav Ramot Naftali (IL)
Assigned to KAHR Medical Ltd., Modiln Makabim-ReUt (IL)
Appl. No. 17/258,170
Filed by KAHR Medical Ltd., Jerusalem (IL)
PCT Filed Jul. 11, 2019, PCT No. PCT/IL2019/050783
§ 371(c)(1), (2) Date Jan. 6, 2021,
PCT Pub. No. WO2020/012486, PCT Pub. Date Jan. 16, 2020.
Claims priority of provisional application 62/696,362, filed on Jul. 11, 2018.
Prior Publication US 2021/0214417 A1, Jul. 15, 2021
Int. Cl. C07K 14/705 (2006.01); A61K 38/00 (2006.01); A61P 35/00 (2006.01); A61K 39/00 (2006.01)
CPC C07K 14/70596 (2013.01) [A61P 35/00 (2018.01); C07K 14/70578 (2013.01); A61K 38/00 (2013.01); A61K 39/00 (2013.01); C07K 2319/21 (2013.01); C07K 2319/50 (2013.01)] 10 Claims
 
1. A SIRPα-4-1BBL fusion protein as set forth in SEQ ID NO: 13.