US 12,134,603 B2
Synthesis method for N-methyl-3-substituted methyl-4-pyrazolamide derivative and N-methyl-3-substituted methyl-4-pyrazolic acid
Shengxue Liu, Zhejiang Province (CN); Yintao Shi, Zhejiang Province (CN); Qiang Gong, Zhejiang Province (CN); Sufang Zhong, Zhejiang Province (CN); Jianjiang Zhang, Zhejiang Province (CN); Xiaoyuan Qian, Zhejiang Province (CN); Fang Guo, Zhejiang Province (CN); Rujun Chen, Zhejiang Province (CN); and Xiaoying Jian, Zhejiang Province (CN)
Assigned to Shaoxing Shangyu Xin Yinbang Biochemical Co., Ltd., Zheijiang (CN)
Filed by Shaoxing Shangyu Xin Yinbang Biochemical Co., Ltd., Zhejiang Province (CN)
Filed on Aug. 16, 2023, as Appl. No. 18/234,629.
Application 18/234,629 is a continuation of application No. PCT/CN2023/088835, filed on Apr. 18, 2023.
Claims priority of application No. 202211020398.6 (CN), filed on Aug. 24, 2022.
Prior Publication US 2024/0083852 A1, Mar. 14, 2024
Int. Cl. C07D 231/14 (2006.01); C07D 409/12 (2006.01)
CPC C07D 231/14 (2013.01) [C07D 409/12 (2013.01)] 15 Claims
 
1. A synthesis method for N-methyl-3-substituted methyl-4-pyrazolamide derivative A, comprising a synthesis route of:

OG Complex Work Unit Chemistry
where, X1, X2 and X3 are one selected from a group consisting of H, F, Cl and Br, respectively; R1 and R2 are one selected from a group consisting of H, 1-4 benzene rings or substituted benzene rings, and aliphatic hydrocarbon group with 1-8 carbon atoms, respectively, and R3 is an aliphatic group having 1-4 carbon atoms.