| CPC B01L 3/502761 (2013.01) [B01L 3/50273 (2013.01); B03C 5/026 (2013.01); B01L 2200/0652 (2013.01); B01L 2400/0415 (2013.01)] | 16 Claims |
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1. A method of sorting particles in a stream of carrier fluid, the method comprising:
introducing a stream of carrier fluid containing a mixture of particles into a stream of sheath fluid flowing within a flow channel so as to focus the carrier fluid into a core stream,
detecting a particle of interest within the core stream of carrier fluid at a point of detection within the flow channel,
applying a potential difference between a first electrode and one or more additional electrodes so as to generate a divergent electric field localised around a tip of the first electrode, wherein the tip of the first electrode is positioned inside of the flow channel or adjacent to the flow channel in a position in which the divergent electric field is experienced by the sheath fluid and carrier fluid within the flow channel, and
subsequently terminating application of the potential difference,
wherein the potential difference is applied in response to the detection of a particle of interest, the applied potential difference being sufficient to generate a centripetal force on a volume of carrier fluid within the divergent electric field, said volume of carrier fluid containing the particle of interest, so as to displace said volume of carrier fluid in a direction having a component orthogonal to the direction of flow, such that the particle of interest is diverted into a desired outlet of the flow channel.
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