US 12,133,982 B2
ECAP based control of electrical stimulation therapy
David A. Dinsmoor, North Oaks, MN (US); Heather Diane Orser, Farmington, MN (US); Scott R. Stanslaski, Shoreview, MN (US); and Erik J. Peterson, Fridley, MN (US)
Assigned to Medtronic, Inc., Minneapolis, MN (US)
Filed by Medtronic, Inc., Minneapolis, MN (US)
Filed on Sep. 24, 2021, as Appl. No. 17/484,848.
Application 17/484,848 is a continuation of application No. 16/449,152, filed on Jun. 21, 2019, granted, now 11,129,989.
Claims priority of provisional application 62/688,221, filed on Jun. 21, 2018.
Prior Publication US 2022/0008730 A1, Jan. 13, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61N 1/36 (2006.01); A61N 1/05 (2006.01)
CPC A61N 1/36139 (2013.01) [A61N 1/36007 (2013.01); A61N 1/36067 (2013.01); A61N 1/36171 (2013.01); A61N 1/36175 (2013.01); A61N 1/0534 (2013.01); A61N 1/0553 (2013.01); A61N 1/36062 (2017.08); A61N 1/36085 (2013.01); A61N 1/36107 (2013.01); A61N 1/36178 (2013.01); A61N 1/36185 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A system comprising:
stimulation generation circuitry configured to:
deliver electrical stimulation therapy to a patient, wherein the electrical stimulation therapy comprises a plurality of informed pulses at a first frequency over a period of time; and
deliver a plurality of control pulses at a second frequency different than the first frequency over the period of time, wherein the plurality of control pulses is interleaved with at least some informed pulses of the plurality of informed pulses; and
processing circuitry configured to:
receive a sensed respective evoked compound action potential (ECAP) after one or more control pulses of the plurality of control pulses and prior to a subsequent informed pulse of the plurality of informed pulses;
adjust, based on at least one respective ECAP, a second amplitude value that at least partially defines the plurality of control pulses of the electrical stimulation therapy;
adjust a first amplitude value that at least partially defines the plurality of informed pulses to maintain a ratio of the second amplitude value to the first amplitude value, the adjusted first amplitude value being different than the adjusted second amplitude value; and
deliver, via the stimulation generation circuitry, the electrical stimulation therapy comprising at least the subsequent informed pulse of the plurality of informed pulses to the patient according to the adjusted first amplitude value and one or more subsequent control pulses of the plurality of control pulses according to the adjusted second amplitude value.