US 12,133,967 B2
Temperature compensation flow-limiting device and elastomeric infusion system
Yuan-Chieh Ding, Taichung (TW)
Assigned to HELIOS BIOMATERIALS LLC., Austin, TX (US)
Filed by HELIOS BIOMATERIALS LLC., Austin, TX (US)
Filed on Jan. 25, 2022, as Appl. No. 17/583,416.
Application 17/583,416 is a continuation of application No. 16/721,138, filed on Dec. 19, 2019, granted, now 11,529,462.
Claims priority of application No. 108134448 (TW), filed on Sep. 24, 2019.
Prior Publication US 2022/0143309 A1, May 12, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61M 5/168 (2006.01); A61M 5/148 (2006.01); A61M 5/152 (2006.01)
CPC A61M 5/16804 (2013.01) [A61M 5/148 (2013.01); A61M 5/152 (2013.01); A61M 2205/0216 (2013.01); A61M 2205/3331 (2013.01); A61M 2205/3372 (2013.01)] 13 Claims
OG exemplary drawing
 
1. A temperature compensation flow-limiting device, configured to be disposed in disposed in an infusion tube of an infusion system to improve instability, caused by temperature change, of the flow velocity of a medicinal solution inside the infusion tube and comprising at least one inner layer and at least one outer layer bonded to an outer side of the inner layer to avoid the inner layer being separated from the outer layer when in use, wherein the coefficient of thermal expansion (CTE) of the inner layer is greater than the coefficient of thermal expansion of the outer layer, and make the flow rate stability coefficient S in the following range: 1.1>S>0.9,

OG Complex Work Unit Math
where Q(T) is the flow rate of the inner layer when the temperature is T, Qo is the flow rate of the inner layer at the initial temperature, C(T) is the inner cavity diameter of the inner layer when the temperature is T, Co is the inner cavity diameter of the inner layer at the initial temperature, E is the thermal expansion coefficient of the outer layer, e is the thermal expansion coefficient of the inner layer, ΔT is the temperature difference, the inner layer expands when the temperature of the fluid inside the infusion path increases, the internal diameter of the inner layer decreases as it is limited by the outer layer, the inner layer shrinks when the temperature of the fluid inside the infusion tube decreases, and the internal diameter of the inner layer increases as it is limited by the outer layer.