US 12,133,963 B2
Syringe pack and method of packing a prefilled syringe
Richard Dumont, Basel (CH); Neil B. Cammish, Basel (CH); Markus Hemminger, Basel (CH); Cyrille Blintz, Basel (CH); and Flora Felsovalyi, Basel (CH)
Assigned to HOFFMANN-LA ROCHE INC., Little Falls, NJ (US)
Appl. No. 17/284,965
Filed by HOFFMANN-LA ROCHE INC., Little Falls, NJ (US)
PCT Filed Oct. 14, 2019, PCT No. PCT/EP2019/077810
§ 371(c)(1), (2) Date Apr. 13, 2021,
PCT Pub. No. WO2020/078920, PCT Pub. Date Apr. 23, 2020.
Claims priority of application No. 18200428 (EP), filed on Oct. 15, 2018.
Prior Publication US 2022/0133981 A1, May 5, 2022
Int. Cl. A61M 5/00 (2006.01); A61M 5/31 (2006.01); A61M 5/315 (2006.01); B65B 5/04 (2006.01)
CPC A61M 5/002 (2013.01) [A61M 5/3137 (2013.01); A61M 5/31505 (2013.01); B65B 5/04 (2013.01); A61M 2005/3139 (2013.01)] 14 Claims
OG exemplary drawing
 
1. A syringe pack with a prefilled syringe and a packaging, the prefilled syringe comprising:
a barrel part with an orifice at a proximal end and a flange portion at a distal end;
a plunger part extending through the distal end of the barrel part into the barrel part;
a stopper adjacent to a proximal end of the plunger part and arranged inside the barrel part such that a dosage chamber is formed inside the barrel part; and
a drug substance arranged inside the dosage chamber,
wherein the prefilled syringe is arranged in the packaging and the packaging is configured to allow external sterilization of the prefilled syringe arranged in the packaging, and
wherein the packaging comprises:
a containment part having a fixing structure which holds the barrel part of the prefilled syringe in a defined fixed position;
a constraining structure which acts on the plunger part of the prefilled syringe to block a movement of the plunger part of the prefilled syringe in a distal direction; and
a cover part tightly closing the containment part,
wherein the constraining structure of the packaging applies a force on the plunger part of the prefilled syringe such that the force applied to the plunger part induces a slight movement of the plunger part towards the dosage chamber and the dosage chamber inside the barrel part of the prefilled syringe is compressed.