US 12,133,739 B2
Use of brain age model in prediction of brain atrophy
Wen-Yih Tseng, Taipei (TW); Yung-Chin Hsu, New Taipei (TW); Lung Chan, New Taipei (TW); Chien-Tai Hong, New Taipei (TW); Yueh-Hsun Lu, New Taipei (TW); Jia-Hung Chen, New Taipei (TW); and Li-Kai Huang, New Taipei (TW)
Assigned to ACROVIZ USA INC., Dover, DE (US); and TAIPEI MEDICAL UNIVERSITY, Taipei (TW)
Filed by AcroViz USA Inc., Dover, DE (US); and Taipei Medical University, Taipei (TW)
Filed on Dec. 14, 2023, as Appl. No. 18/539,555.
Application 18/539,555 is a continuation of application No. 18/225,312, filed on Jul. 24, 2023, granted, now 11,883,184.
Application 18/225,312 is a continuation in part of application No. 17/992,005, filed on Nov. 22, 2022, granted, now 11,751,798, issued on Sep. 12, 2023.
Application 17/992,005 is a continuation of application No. 17/704,287, filed on Mar. 25, 2022, granted, now 11,589,800, issued on Feb. 28, 2023.
Claims priority of provisional application 63/216,028, filed on Jun. 29, 2021.
Prior Publication US 2024/0206801 A1, Jun. 27, 2024
Int. Cl. A61B 5/00 (2006.01); A61B 5/055 (2006.01); G06T 7/00 (2017.01)
CPC A61B 5/4088 (2013.01) [A61B 5/055 (2013.01); A61B 5/7275 (2013.01); G06T 7/0012 (2013.01); G06T 2207/10092 (2013.01); G06T 2207/30016 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A method of determining and predicting a brain atrophy condition for an individual using the individual's predicted age difference (PAD), the method comprising:
(1) acquiring at least one brain image of the individual;
(2) processing the brain image to obtain at least one feature of the brain image;
(3) generating a PAD value of the individual based on the at least one feature of the image; and
(4) determining a brain atrophy condition of the individual based on the PAD value.