US 12,133,726 B2
Detection of gait activity
Mattia Zanon, Zurich (CH); Lorenza Angelini, Riehen (CH); and Dimitar Yuriev Stanev, Basel (CH)
Filed by Hoffmann-La Roche Inc., Little Falls, NJ (US)
Filed on Jan. 12, 2024, as Appl. No. 18/411,567.
Claims priority of application No. 23156442 (EP), filed on Feb. 14, 2023.
Prior Publication US 2024/0268709 A1, Aug. 15, 2024
Int. Cl. A61B 5/11 (2006.01); A61B 5/00 (2006.01)
CPC A61B 5/112 (2013.01) [A61B 5/4076 (2013.01); A61B 5/4842 (2013.01); A61B 5/4848 (2013.01); A61B 5/6802 (2013.01); A61B 5/725 (2013.01); A61B 5/726 (2013.01); A61B 2562/0219 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A system, comprising:
at least one data processor; and
at least one memory storing instructions, which when executed by the at least one data processor, result in operations comprising:
receiving, from one or more sensors configured to be located on a subject, a signal representative of a gait activity of the subject;
identifying one or more directional components of the signal, the one or more directional components including a medio-lateral component and an antero-posterior component, and the one or more directional components being independent of an orientation of the one or more sensors on the subject;
validating, based at least on a medio-lateral autocorrelation of the medio-lateral component and an antero-posterior autocorrelation of the antero-posterior component, the medio-lateral component and the antero-posterior component;
in response to a failure to validate the medio-lateral component and the antero-posterior component, swapping the medio-lateral component and the antero-posterior component;
extracting, based at least on the one or more directional components of the signal, one or more gait features from the signal; and
determining, based at least on the one or more gait features, at least one of a diagnosis, a progression, a treatment, and a treatment response for a neurological dysfunction.