US 12,133,713 B2
Clinical intravital microscope
Joseph Skitzki, Buffalo, NY (US)
Assigned to Health Research, Inc., Buffalo, NY (US)
Filed by Health Research, Inc., Buffalo, NY (US)
Filed on May 25, 2020, as Appl. No. 16/882,602.
Application 16/882,602 is a continuation of application No. 15/307,923, abandoned, previously published as PCT/US2015/029242, filed on May 5, 2015.
Claims priority of provisional application 61/988,626, filed on May 5, 2014.
Prior Publication US 2020/0281473 A1, Sep. 10, 2020
Int. Cl. A61B 5/00 (2006.01); A61B 5/02 (2006.01); A61B 5/026 (2006.01); G02B 7/00 (2021.01); G02B 21/00 (2006.01); G02B 21/02 (2006.01); G02B 21/36 (2006.01); H04N 5/91 (2006.01); H04N 7/18 (2006.01)
CPC A61B 5/0071 (2013.01) [A61B 5/0077 (2013.01); A61B 5/02007 (2013.01); A61B 5/0261 (2013.01); G02B 7/001 (2013.01); G02B 21/0012 (2013.01); G02B 21/0076 (2013.01); G02B 21/025 (2013.01); G02B 21/365 (2013.01); H04N 5/91 (2013.01); H04N 7/183 (2013.01); A61B 5/02042 (2013.01); A61B 2505/05 (2013.01); A61B 2560/0437 (2013.01)] 17 Claims
OG exemplary drawing
 
1. An intravital microscope system for observing tissues of a human patient in real-time during a medical procedure, the system comprising:
a heavy base having one or more wheels for moving the base on a support surface;
an arm having a proximal and a distal end, the proximal end of the arm supported by the base, the arm extending horizontally from the base;
an intravital microscope having an eyepiece and an objective, the intravital microscope mounted on the arm, wherein the intravital microscope has a magnification between about 100× and 200×;
a video camera operatively associated with the intravital microscope;
a surface for supporting the human patient underneath the intravital microscope;
a processor for receiving and storing video images from the camera and for minimizing motion artifact; and,
wherein the base and the processor for minimizing motion artifact are configured and arranged to provide visualization of tumors in situ in the human patient in real time to generate dynamic data.