| CPC G06T 7/80 (2017.01) [G06T 7/0002 (2013.01); G06T 2207/10056 (2013.01); G06T 2207/30168 (2013.01)] | 24 Claims |

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1. A system for automated calibration for a scanning system, the system comprising:
an imaging reference located on a scanning stage of a scanner;
an optical sensor, wherein the optical sensor is configured to:
capture a first reference image of the imaging reference prior to scanning a target; and
capture a second reference image of the imaging reference after scanning the target;
at least a processor; and
a memory communicatively connected to the at least a processor, wherein the memory contains instructions configuring the at least a processor to:
receive the first reference image and the second reference image from the optical sensor;
determine one or more image metrics of each of the first reference image and the second reference image as a function of reference features of the imaging references in the first reference image and the second reference image;
detect a reference deviation in the one or more image metrics between the first reference image and the second reference image;
classify the reference deviation to a deviation cause of the reference deviation; and
generate an alert signal as a function of the deviation cause, wherein the alert signal is configured to initiate an automated calibration process.
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