| CPC G01R 33/5608 (2013.01) [G01R 33/4818 (2013.01); G01R 33/5601 (2013.01); G01R 33/56509 (2013.01)] | 20 Claims |
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1. A computer-implemented method of reconstructing a dynamic series of magnetic resonance images of a patient, the computer-implemented method comprising:
acquiring, by an imaging device, first k-space data of at least one proton density weighted image of a patient;
acquiring, by the imaging device, second k-space data of a dynamic series of magnetic resonance images of the patient, the dynamic series of magnetic resonance images being acquired over at least one of successive respiratory cycles or successive cardiac cycles;
reconstructing the at least one proton density weighted image based on the first k-space data to obtain at least one reconstructed proton density weighted image;
generating a dynamic series of processing images, the dynamic series of processing images including at least two processing images, and the generating the dynamic series of processing images includes reconstructing the at least two processing images based on the second k-space data and a temporal regularization;
estimating a motion between the at least two processing images to obtain an estimated motion;
applying a corresponding motion correction to the each respective processing image among the at least two processing images based on the estimated motion to generate a dynamic series of motion corrected images;
registering the at least one reconstructed proton density weighted image to at least one motion corrected image among the dynamic series of motion corrected images;
applying a signal intensity correction to the dynamic series of motion corrected images based on the at least one reconstructed proton density weighted image to obtain a signal intensity corrected dynamic series of motion corrected images; and
providing the signal intensity corrected dynamic series of motion corrected images,
wherein
the acquiring the first k-space data is performed before a contrast agent is administered to the patient or before arrival of the contrast agent in a myocardium,
the acquiring the second k-space data is performed after the contrast agent is administered to the patient or after the arrival of the contrast agent in the myocardium,
the acquiring the second k-space data acquires the second k-space data for an acquiring time interval after an administering time of the contrast agent, and
the registering the at least one reconstructed proton density weighted image to the at least one motion corrected image is based on a first motion corrected image acquired in a last third of the acquiring time interval the first motion corrected image being among the dynamic series of motion corrected images.
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