US 12,461,097 B2
Patterned dried blood spot cards and related articles and methods
Charles R. Mace, Winchester, MA (US); Jessica E. Schilling, Bloomington, MN (US); Syrena C. Fernandes, Somerville, MA (US); and Keith Baillargeon, Medford, MA (US)
Assigned to Trustees of Tufts College, Medford, MA (US)
Filed by Trustees of Tufts College, Medford, MA (US)
Filed on Jun. 13, 2024, as Appl. No. 18/742,297.
Application 18/742,297 is a division of application No. 17/252,511, previously published as PCT/US2019/037913, filed on Jun. 19, 2019.
Claims priority of provisional application 62/688,707, filed on Jun. 22, 2018.
Prior Publication US 2024/0337653 A1, Oct. 10, 2024
Int. Cl. G01N 33/72 (2006.01); G01N 33/543 (2006.01); G01N 33/80 (2006.01)
CPC G01N 33/54386 (2013.01) [G01N 33/72 (2013.01); G01N 33/80 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A fluidic device, comprising:
a first layer comprising a porous, absorbent material, wherein the first layer comprises a central region in fluidic communication with an environment external to the fluidic device, a first channel in fluidic communication with the central region, and a second channel in fluidic communication with the central region, wherein the first and second channels extend radially outwards from the central region, wherein the first channel comprises a first sample region that extends laterally outwards from the rest of the first channel such that the first sample region is the widest part of the first channel, wherein the second channel comprises a second sample region that extends laterally outwards from the rest of the second channel such that the second sample region is the widest part of the second channel, and wherein the first and second sample regions are equidistant from the central region; and
a second, filtration layer configured to separate blood cells from plasma, wherein the second layer comprises synthetic fibers and/or glass fibers, wherein the second layer is positioned between the environment external to the fluidic device and the central region, wherein the second layer does not cover the entirety of the first layer, and wherein the second layer is centered over the central region.