US 12,461,064 B2
Magnetic control of molecule translocation speed through a nanopore
Justin P. Kinney, San Jose, CA (US); and Daniel Bedau, San Jose, CA (US)
Assigned to Western Digital Technologies, Inc., San Jose, CA (US)
Filed by Western Digital Technologies, Inc., San Jose, CA (US)
Filed on Aug. 3, 2023, as Appl. No. 18/364,506.
Claims priority of provisional application 63/510,036, filed on Jun. 23, 2023.
Prior Publication US 2024/0426778 A1, Dec. 26, 2024
Int. Cl. G01N 27/447 (2006.01); C12Q 1/6869 (2018.01)
CPC G01N 27/44786 (2013.01) [C12Q 1/6869 (2013.01); G01N 27/44791 (2013.01)] 25 Claims
OG exemplary drawing
 
1. A system for controlling a translocation speed of a molecule through a nanopore, the system comprising:
a fluid chamber containing a solution having a magnetic susceptibility that is different from a magnetic susceptibility of the molecule;
the nanopore situated in the fluid chamber; and
at least one magnetic component configured to create a magnetic field gradient within the fluid chamber to control the translocation speed of the molecule through the nanopore,
wherein (i) the solution is a paramagnetic solution, (ii) the molecule is paramagnetic, or (iii) both (i) and (ii).