US 12,461,012 B2
Particle analysis system having autofluorescence spectrum correction
Yasuharu Yamauchi, Tokyo (JP); Koji Futamura, Tokyo (JP); and Gregory Veltri, Denver, CO (US)
Assigned to Sony Group Corporation, Tokyo (JP)
Appl. No. 17/620,651
Filed by Sony Group Corporation, Tokyo (JP)
PCT Filed Jun. 19, 2020, PCT No. PCT/JP2020/024072
§ 371(c)(1), (2) Date Dec. 17, 2021,
PCT Pub. No. WO2020/262215, PCT Pub. Date Dec. 30, 2020.
Claims priority of provisional application 62/865,616, filed on Jun. 24, 2019.
Prior Publication US 2022/0317019 A1, Oct. 6, 2022
Int. Cl. G01N 15/14 (2024.01); G01N 15/10 (2024.01); G01N 21/01 (2006.01); G01N 21/64 (2006.01)
CPC G01N 15/1459 (2013.01) [G01N 21/01 (2013.01); G01N 21/6402 (2013.01); G01N 2015/1006 (2013.01); G01N 2021/6419 (2013.01); G01N 2021/6441 (2013.01)] 13 Claims
OG exemplary drawing
 
1. A particle analysis system comprising:
a light detector that acquires light generated by irradiating a particle with excitation light; and
an information processor that outputs a spectral plot including spectrum information of a plurality of autofluorescence populations specified in a two-dimensional plot of measurement data corresponding to the acquired light and spectrum information of the measurement data, wherein
the information processor outputs spectrum information of the plurality of autofluorescence populations as a list and records the spectrum information of the autofluorescence populations specified in the list as an autofluorescence reference spectrum, and
one or more of the plurality of autofluorescence populations is selected from the list to be used in a fluorescence separation process, and
the information processor performs the fluorescence separation process based on the selected autofluorescence population or populations from the list, thereby removing the spectrum information of the selected autofluorescence population or populations from the list from the spectrum information of the measurement data.