	US 12,461,007 B2
	CD34 stem cell mimics
Jeffrey Kim, Berkeley, CA (US); Anh Tuan Nguyen, San Francisco, CA (US); Subhanip Biswas, Emeryville, CA (US); and Kanwal Palla, Oakland, CA (US)
Assigned to Slingshot Biosciences, Inc., Emeryville, CA (US)
Filed by Slingshot Biosciences, Inc., Emeryville, CA (US)
Filed on Aug. 28, 2024, as Appl. No. 18/817,528.
Claims priority of provisional application 63/535,233, filed on Aug. 29, 2023.
Prior Publication US 2025/0076175 A1, Mar. 6, 2025
Int. Cl. G01N 15/10 (2024.01); G01N 33/58 (2006.01)

CPC G01N 15/1012 (2013.01) [G01N 33/582 (2013.01); G01N 2015/1014 (2024.01); G01N 2333/70589 (2013.01); G01N 2333/70596 (2013.01)]

28 Claims

1. A composition comprising a first population of hydrogel beads comprising:

a) a polymerized monomer and a bifunctional monomer; and

b) a cell surface biomarker profile comprising:

i) a CD34 extracellular domain and a CD45 extracellular domain,

wherein the CD34 extracellular domain comprises a sequence comprising at least 90% identity with SEQ ID NO: 1, and the CD45 extracellular domain comprises a sequence comprising at least 90% identity with SEQ ID NO: 10.