	US 12,460,049 B2
	Azide-functionalized copolymers
Stefan Zuercher, Zurich (CH); Tobias Komsthoeft, Zurich (CH); Samuele Tosatti, Duebendorf (CH); and Lucca Trachsel, Oberrieden (CH)
Assigned to SUSOS AG, Duebendorf (CH)
Appl. No. 18/832,730
Filed by SUSOS AG, Duebendorf (CH)
PCT Filed Jan. 25, 2023, PCT No. PCT/EP2023/051836 § 371(c)(1), (2) Date Jul. 24, 2024, PCT Pub. No. WO2023/144228, PCT Pub. Date Aug. 3, 2023.
Claims priority of application No. 22153331 (EP), filed on Jan. 25, 2022.
Prior Publication US 2025/0101177 A1, Mar. 27, 2025
Int. Cl. C07D 263/00 (2006.01); A61K 47/59 (2017.01); C07D 265/00 (2006.01); C08G 69/08 (2006.01); C08G 69/42 (2006.01); C08G 73/02 (2006.01); C08G 77/452 (2006.01); C09D 177/02 (2006.01)

CPC C08G 69/42 (2013.01) [A61K 47/595 (2017.08); C08G 69/08 (2013.01); C09D 177/02 (2013.01)]

20 Claims

1. A copolymer comprising at least a first and a second monomer unit, wherein:

the first and the second monomer unit are different from each other;

the first monomer unit is selected from the group consisting of compounds 202, 203, 204, 205, 206, 207, 302, 303, 304, 305, 306, and 307


No.	Monomer unit	No.	Monomer unit

202		302

203		303

204		304

205		305

206		306

207		307

and the second monomer unit is selected from the group consisting of 2-methyl-4,5-dihydro-1,3-oxazole, 2-ethyl-4,5-dihydro-1,3-oxazole, 2-methyl-5,6-dihydro-4H-1,3-oxazine and 2-ethyl-5-6-dihydro-4H-1,3-oxazine with the proviso that

if the second monomer unit is 2-ethyl-4,5-dihydro-1,3-oxazole, the first monomer unit is selected from the group consisting of compounds 202, 204 and 205,

and if the second monomer unit is 2-ethyl-5-6-dihydro-4H-1,3-oxazine, the first monomer unit is selected from the group consisting of compounds 302, 304 and 305; and

the copolymer is protein resistant.