US 12,460,010 B2
Antibodies that bind TNFRSF25
Suresh De Silva, Austin, TX (US); Mahmud Hussain, Austin, TX (US); Anne Lai, Austin, TX (US); Derek Franklin, Austin, TX (US); and Taylor Schreiber, Austin, TX (US)
Assigned to SHATTUCK LABS, INC., Austin, TX (US)
Filed by SHATTUCK LABS, INC., Austin, TX (US)
Filed on May 5, 2025, as Appl. No. 19/198,507.
Application 19/198,507 is a continuation of application No. 19/036,915, filed on Jan. 24, 2025, granted, now 12,319,742.
Claims priority of provisional application 63/720,903, filed on Nov. 15, 2024.
Claims priority of provisional application 63/706,966, filed on Oct. 14, 2024.
Claims priority of provisional application 63/700,056, filed on Sep. 27, 2024.
Claims priority of provisional application 63/677,519, filed on Jul. 31, 2024.
Claims priority of provisional application 63/570,593, filed on Mar. 27, 2024.
Claims priority of provisional application 63/624,600, filed on Jan. 24, 2024.
Prior Publication US 2025/0277049 A1, Sep. 4, 2025
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 16/00 (2006.01); A61K 39/395 (2006.01); A61P 1/04 (2006.01); A61P 29/00 (2006.01); C07K 16/28 (2006.01)
CPC C07K 16/2878 (2013.01) [A61P 1/04 (2018.01); A61P 29/00 (2018.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/56 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01)] 14 Claims
 
1. A monoclonal antibody or antibody fragment that binds to tumor necrosis factor receptor super-family 25 (TNFRSF25) comprising a heavy chain comprising the amino acid sequence of SEQ ID NO: 134 and a light chain comprising the amino acid sequence of SEQ ID NO: 57.