	US 12,460,007 B2
	Antibodies that bind to C-type lectin domain family 2 member D (CLEC2D)
Kavitha Iyer Rodrigues, Bangalore (IN); Maloy Ghosh, Bangalore (IN); Sunit Maity, Bangalore (IN); Yogendra Manjunath Bangalore Muniraju, Bangalore (IN); Sathyabalan Murugesan, Bangalore (IN); Sanghamitra Bhattacharjee, Bangalore (IN); Vivek Halan, Bangalore (IN); Subhra Prakash Chakrabarty, Bangalore (IN); Ashvini Kumar Dubey, Bangalore (IN); Anurag Tiwari, Bangalore (IN); Kirthana Mysore Vasudevarao Sindhe, Bangalore (IN); Pallavi Lahiri, Bangalore (IN); Sahana Bhima Rao, Bangalore (IN); Prachi, Bangalore (IN); Shruti Srivastava, Bangalore (IN); Rao Shreesha Ramesh, Bangalore (IN); Bharath Ravindra Shenoy, Bangalore (IN); Nikitha Markanda, Bangalore (IN); Bhagyashree Dikey, Bangalore (IN); and Bairavabalakumar Natarajan, Bangalore (IN)
Assigned to Zumutor Biologics Inc., Cambridge, MA (US)
Filed by Zumutor Biologics Inc., Cambridge, MA (US)
Filed on May 8, 2023, as Appl. No. 18/314,117.
Application 18/314,117 is a continuation of application No. 16/786,391, filed on Feb. 10, 2020, granted, now 11,827,710.
Claims priority of application No. 201941005395 (IN), filed on Feb. 11, 2019.
Prior Publication US 2024/0010733 A1, Jan. 11, 2024
Int. Cl. C07K 16/28 (2006.01); A61K 39/00 (2006.01); A61K 40/11 (2025.01); A61K 40/15 (2025.01); A61K 40/42 (2025.01); A61P 35/00 (2006.01); C12N 5/071 (2010.01); C12N 15/10 (2006.01)

CPC C07K 16/2851 (2013.01) [A61K 40/11 (2025.01); A61K 40/15 (2025.01); A61K 40/42 (2025.01); A61P 35/00 (2018.01); C12N 5/0602 (2013.01); C12N 15/1055 (2013.01); A61K 2039/505 (2013.01); C07K 2317/41 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/734 (2013.01); C07K 2317/92 (2013.01)]

20 Claims

1. An isolated antibody that binds to C-Type Lectin Domain Family 2 Member D (CLEC2D) or an antigen-binding fragment thereof, wherein the isolated antibody or antigen-binding fragment thereof comprises a variable heavy chain (VH) amino acid sequence and a variable light chain (VL) amino acid sequence selected from the group consisting of:

a. a VH amino acid sequence of SEQ ID NO: 65 and

a VL amino acid sequence of SEQ ID NO: 281, and

a VH amino acid sequence of SEQ ID NO: 99 and

a VL amino acid sequence of SEQ ID NO: 315;

b. a VH amino acid sequence of SEQ ID NO: 91 and

a VL amino acid sequence of SEQ ID NO: 307,

a VH amino acid sequence of SEQ ID NO: 98 and

a VL amino acid sequence of SEQ ID NO: 314,

a VH amino acid sequence of SEQ ID NO: 84 and

a VL amino acid sequence of SEQ ID NO: 300,

a VH amino acid sequence of SEQ ID NO: 88 and

a VL amino acid sequence of SEQ ID NO: 304,

a VH amino acid sequence of SEQ ID NO: 96 and

a VL amino acid sequence of SEQ ID NO: 312,

a VH amino acid sequence of SEQ ID NO: 17 and

a VL amino acid sequence of SEQ ID NO: 233, and

a VH amino acid sequence of SEQ ID NO: 8 and

a VL amino acid sequence of SEQ ID NO: 224.