US 12,459,978 B2
Tag protein for increasing water solubility and heat stability of target protein, and fusion protein comprising same
Dae-Hyuk Kweon, Suwon-si (KR); Yun-Jeong Park, Suwon-si (KR); Ki-Jun Jeong, Daejeon (KR); and Yoon-Jin Bae, Hwaseong-si (KR)
Assigned to MVRIX Co., Ltd., Hwaseong-si (KR)
Appl. No. 17/761,709
Filed by MVRIX Co., Ltd., Hwaseong-si (KR)
PCT Filed Sep. 18, 2020, PCT No. PCT/KR2020/012640
§ 371(c)(1), (2) Date Mar. 18, 2022,
PCT Pub. No. WO2021/054774, PCT Pub. Date Mar. 25, 2021.
Claims priority of application No. 10-2019-0116019 (KR), filed on Sep. 20, 2019.
Prior Publication US 2022/0340628 A1, Oct. 27, 2022
Int. Cl. C07K 14/47 (2006.01); C12N 9/02 (2006.01); C12N 9/10 (2006.01); C12N 15/63 (2006.01)
CPC C07K 14/4702 (2013.01) [C12N 15/63 (2013.01); C07K 2319/74 (2013.01)] 5 Claims
 
1. A fusion protein comprising:
a target protein; and
a protein tag linked to the target protein, the protein tag comprising an octameric transcription factor-1 (Oct-1) protein,
wherein the Oct-1 protein is encoded by the nucleotide sequence of SEQ ID NO: 1.