US 12,459,969 B2
Process for the preparation of trenbolone and/or trenbolone acetate
Anna Rencurosi, Montecchio Maggiore Vicenza (IT)
Assigned to F.I.S.—FABBRICA ITALIANA SINTETICI S.P.A., Montecchio Maggiore Vicenza (IT)
Appl. No. 18/253,339
Filed by F.I.S.—FABBRICA ITALIANA SINTETICI S.P.A., Montecchio Maggiore Vicenza (IT)
PCT Filed Nov. 18, 2021, PCT No. PCT/EP2021/082209
§ 371(c)(1), (2) Date May 17, 2023,
PCT Pub. No. WO2022/106574, PCT Pub. Date May 27, 2022.
Claims priority of application No. 20208607 (EP), filed on Nov. 19, 2020; application No. 20208625 (EP), filed on Nov. 19, 2020; and application No. 21163673 (EP), filed on Mar. 19, 2021.
Prior Publication US 2024/0025941 A1, Jan. 25, 2024
Int. Cl. C07J 1/00 (2006.01)
CPC C07J 1/0074 (2013.01) [C07J 1/00 (2013.01)] 13 Claims
 
1. A process for the preparation of compound of formula (I):

OG Complex Work Unit Chemistry
wherein R is H or Ac;
comprising reacting a compound of formula (II):

OG Complex Work Unit Chemistry
wherein R is H or Ac;
with an oxidant agent in an organic solvent, wherein the reaction is performed in presence of a acid.