US 12,459,924 B2
Process for manufacturing alkyleneamine compounds
Eike Nicolas Kantzer, Uddevalla (SE); Karl Fredrik Lake, Södertälje (SE); Robert Kristoffer Berg, Rönninge (SE); Rolf Krister Edvinsson, Partille (SE); Antoon Jacob Berend Ten Kate, Arnhem (NL); Ina Ehlers, Stenungsund (SE); Hendrik Van Dam, Ede (NL); Michiel Jozef Thomas Raaijmakers, Deventer (NL); Rens Veneman, Amersfoort (NL); Slavisa Jovic, Utrecht (NL); and Lawien Feisal Zubeir, Deventer (NL)
Assigned to NOURYON CHEMICALS INTERNATIONAL B.V., Arnhem (NL)
Appl. No. 17/310,499
Filed by NOURYON CHEMICALS INTERNATIONAL B.V., Arnhem (NL)
PCT Filed Feb. 4, 2020, PCT No. PCT/EP2020/052777
§ 371(c)(1), (2) Date Aug. 6, 2021,
PCT Pub. No. WO2020/161146, PCT Pub. Date Aug. 13, 2020.
Claims priority of application No. 19155974 (EP), filed on Feb. 7, 2019.
Prior Publication US 2022/0194927 A1, Jun. 23, 2022
Int. Cl. C07D 403/12 (2006.01); C07C 209/62 (2006.01); C07D 233/36 (2006.01); C07D 241/04 (2006.01)
CPC C07D 403/12 (2013.01) [C07C 209/62 (2013.01); C07D 233/36 (2013.01); C07D 241/04 (2013.01)] 10 Claims
 
1. A process comprising the steps of:
in a reaction medium reacting:
a urea adduct of diethylene triamine having the following structure:

OG Complex Work Unit Chemistry
with ethylene dichloride to form a hydrochloride salt of a 1,5-diurea adduct of pentaethylenehexamine, and
reacting the hydrochloride salt with a base to form the 1,5-diurea adduct of pentaethylenehexamine having the following structure:

OG Complex Work Unit Chemistry