US 12,459,909 B2
Nitrosation reagents and methods
Ryan D. Baxter, Merced, CA (US); and Jordan Galloway, Merced, CA (US)
Assigned to The Regents of the University of California, Oakland, CA (US)
Appl. No. 17/928,519
Filed by The Regents of the University of California, Oakland, CA (US)
PCT Filed Jun. 17, 2021, PCT No. PCT/US2021/037860
§ 371(c)(1), (2) Date Nov. 29, 2022,
PCT Pub. No. WO2021/257849, PCT Pub. Date Dec. 23, 2021.
Claims priority of provisional application 63/040,803, filed on Jun. 18, 2020.
Prior Publication US 2023/0242495 A1, Aug. 3, 2023
Int. Cl. C07D 275/06 (2006.01); C07B 43/02 (2006.01); C07C 243/06 (2006.01); C07D 205/08 (2006.01); C07D 207/50 (2006.01); C07D 209/38 (2006.01); C07D 211/98 (2006.01); C07D 213/34 (2006.01); C07D 233/80 (2006.01); C07D 239/26 (2006.01); C07D 241/08 (2006.01); C07D 277/14 (2006.01); C07D 277/30 (2006.01); C07D 295/28 (2006.01); C07D 317/24 (2006.01); C07D 317/54 (2006.01); C07D 317/56 (2006.01); C07D 319/04 (2006.01); C07D 319/20 (2006.01); C07D 453/04 (2006.01); C07D 495/04 (2006.01)
CPC C07D 275/06 (2013.01) 20 Claims
 
1. A compound of formula (I):

OG Complex Work Unit Chemistry
wherein:
n is 0 to 4,
N′ is 14N or 15N, and
R1, R2, and each R3 are each independently selected from hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, heterocycle, substituted heterocycle, aryl, substituted aryl, heteroaryl, substituted heteroaryl, halo, and hydroxyl.