| CPC B29C 66/53245 (2013.01) [A61F 2/2412 (2013.01); A61F 2/2415 (2013.01); A61F 2/2418 (2013.01); A61F 2/2433 (2013.01); A61F 2210/0076 (2013.01); A61F 2230/0069 (2013.01); A61F 2240/001 (2013.01); A61F 2250/0069 (2013.01)] | 19 Claims |

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1. A prosthetic heart valve, comprising:
an annular frame that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration, the frame having an inflow end and an outflow end, and defining a longitudinal axis along a lumen of the prosthetic heart valve when the prosthetic heart valve is in the expanded configuration;
a leaflet structure positioned within the frame and secured thereto; and
a laminate sealing member comprising a plurality of layers heat-bonded together to encapsulate at least a portion of the frame;
wherein the laminate sealing member extends along the longitudinal axis in an upstream direction and doubles back toward the outflow end of the frame at a fold line to form a cuff, and an edge portion of the laminate sealing member is secured to a main portion of the laminate sealing member downstream of the fold line such that the cuff forms an inflow end of the laminate sealing member; and
wherein an inflow edge of the leaflet structure is offset from the inflow end of the frame in a downstream direction toward the outflow end of the frame.
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