US 12,458,817 B2
Wearable closed loop TUS system
Christopher Daft, Tucson, AZ (US); and Bicheng Wu, Palo Alto, CA (US)
Assigned to Sanmai Technologies, PBC, Sunnyvale, CA (US)
Filed by Sanmai Technologies, PBC, Sunnyvale, CA (US)
Filed on Oct. 18, 2024, as Appl. No. 18/920,615.
Claims priority of provisional application 63/601,577, filed on Nov. 21, 2023.
Prior Publication US 2025/0161718 A1, May 22, 2025
Int. Cl. A61N 7/00 (2006.01); B06B 1/06 (2006.01); G06F 21/44 (2013.01)
CPC A61N 7/00 (2013.01) [B06B 1/0622 (2013.01); G06F 21/44 (2013.01); A61N 2007/0026 (2013.01); A61N 2007/0056 (2013.01); A61N 2007/0082 (2013.01); B06B 2201/76 (2013.01)] 22 Claims
OG exemplary drawing
 
1. A system comprising:
a headband device comprising one or more transcranial ultrasound (TUS) tiles, wherein each of the TUS tiles further comprises a plurality of transducer elements connected to an integrated circuit, and wherein the TUS tiles are arranged in an array that are electrically coupled with adjacent tiles in the array; and
a computing device in wireless communication with the headband device, the computing device generating a stimulation signal specification and transmitting the stimulation signal specification to the headband device, wherein the TUS tiles output the stimulation signal via the headband device.
 
18. A method comprising:
placing a headband device comprising a plurality of transcranial ultrasound (TUS) tiles on a subject scalp;
obtaining TUS parameters from a memory, the TUS parameters specifying an operational mode of the TUS tiles;
obtaining skull characterization parameters from the TUS tiles by operating the TUS tiles in a channel mode;
calculating skull aberration correction parameters based on the skull characterization parameters;
adjusting the TUS parameters based on the skull aberration correction parameters; and
generating a stimulation signal based on the adjusted TUS parameters, wherein the TUS files emit the stimulation signal via the headband device.