US 12,458,813 B2
Implantable device and method of brain biomodulation
Alexis Bruhat, New York, NY (US); Turner Baker, New York, NY (US); Christopher Kellner, New York, NY (US); and Anthony Costa, New York, NY (US)
Assigned to Icahn School of Medicine at Mount Sinai, New York, NY (US)
Appl. No. 18/038,362
Filed by Icahn School of Medicine at Mount Sinai, New York, NY (US)
PCT Filed Nov. 23, 2021, PCT No. PCT/US2021/060508
§ 371(c)(1), (2) Date May 23, 2023,
PCT Pub. No. WO2022/115425, PCT Pub. Date Jun. 2, 2022.
Claims priority of provisional application 63/117,784, filed on Nov. 24, 2020.
Prior Publication US 2024/0001141 A1, Jan. 4, 2024
Int. Cl. A61N 5/06 (2006.01)
CPC A61N 5/0622 (2013.01) [A61N 5/0601 (2013.01); A61N 5/0618 (2013.01); A61N 2005/0632 (2013.01); A61N 2005/0647 (2013.01); A61N 2005/0651 (2013.01)] 23 Claims
OG exemplary drawing
 
1. An intracranial photobiomodulation system (IPS) comprising:
a removeable light therapy implant; and a permanent sheath,
wherein the removeable light therapy implant is adapted to be removably secured to the sheath and has (i) a support arm having a proximal end and a distal end, and (ii) at least one light source located along the support arm, the at least one light source configured to emit light of at least one wavelength and at least one intensity for a set timing and duration, the permanent sheath comprising a shell and a sleeve, the shell being adapted to be permanently secured to a scalp of a patient, the sleeve being made of a light transmissive material and having a proximal opening and a distal closed tip, the proximal opening adapted to removably receive the support arm and light source of the removeable light therapy implant such that the permanent sheath surrounds the support arm and the light source.
 
23. An intracranial photobiomodulation system (IPS) comprising:
a permanent sheath that includes a first proximal end portion that has a recessed section and a hollow elongated flexible sleeve that is integral to and extends outwardly from the first proximal end portion, the recessed section having a through hole that forms an entrance into the hollow elongated flexible sleeve, the first proximal end portion being configured to be permanently secured to a scalp of a patient, the hollow elongated flexible sleeve being formed of a light transmissive material;
a removeable light therapy implant that is adapted to be removably coupled to the permanent sheath and is at least partially contained within the hollow elongated flexible sleeve, the removeable light therapy implant having a second proximal end portion and a support arm that extends outwardly from the second proximal end portion, the removeable light therapy implant including at least one light source located along the support arm, the at least one light source configured to emit light of at least one wavelength and at least one intensity, wherein in a fully installed position, the second proximal end portion is received within the recessed section and the support arm and light source of the removeable light therapy implant are received within the hollow elongated sleeve such that the hollow elongated flexible sleeve surrounds the support arm and the light source, wherein the second proximal end portion includes an RFID receiver that is configured to power the at least one light source; and
a headband device configured for placement about a head of the patient such that the headband device surrounds the permanent sheath and the removable light therapy implant contained therein, the headband device including an RFID transmitter circuit positioned internally along the circumference of the headband device that is operative to wirelessly transmit electrical energy to the RFID receiver of the removeable light therapy implant.