US 12,458,671 B2
Product for the treatment of dysbiosis
Daniel Greff, Mere (FR)
Assigned to BIOPASS, Luxembourg (LU)
Appl. No. 17/421,154
Filed by Biopass, Luxembourg (LU)
PCT Filed Jan. 13, 2020, PCT No. PCT/EP2020/050717
§ 371(c)(1), (2) Date Jul. 7, 2021,
PCT Pub. No. WO2020/144380, PCT Pub. Date Jul. 16, 2020.
Claims priority of application No. 1900279 (FR), filed on Jan. 11, 2019.
Prior Publication US 2022/0080000 A1, Mar. 17, 2022
Int. Cl. A61K 35/741 (2015.01); A61K 35/744 (2015.01); A61K 47/10 (2017.01); A61K 47/32 (2006.01); A61P 17/04 (2006.01)
CPC A61K 35/741 (2013.01) [A61K 35/744 (2013.01); A61K 47/10 (2013.01); A61K 47/32 (2013.01); A61P 17/04 (2018.01)] 20 Claims
 
1. A method for the topical treatment of an area of skin of a person suffering from dysbiosis, said person having an initial healthy skin microbiota before suffering from dysbiosis, said method comprising in sequence:
a step of applying, on the area of skin, a product having a pH between 5.5 and 6.5 and comprising at least 90% by mass of a mixture consisting of water, glycerol, at least one crosslinked polyacrylate, and at least one polyol different from glycerol, and
a step of cleansing said product in order to remove the product after leaving the product to act for a sufficient time,
a step of applying, on the area of skin to which the product was applied, a composition being a healthy skin microbiota transplantation composition comprising at least one biological material selected from the group consisting of a bacterium, an extract of a bacterium or an extract of a culture medium of a bacterium,
wherein the product is free of any biological material, and
wherein a time period between the step of applying the product and the step of applying the composition is in a range of from 5 minutes to 1 hour.