	US 12,458,647 B2
	Macrocyclic derivative and use thereof
Yang Zhang, Shanghai (CN); Kai Zhou, Shanghai (CN); Fen Jiang, Shanghai (CN); Li Zhang, Shanghai (CN); Xiao Liu, Shanghai (CN); Zheng Wang, Shanghai (CN); Kevin X. Chen, Shanghai (CN); Jian Li, Shanghai (CN); and Shuhui Chen, Shanghai (CN)
Assigned to Guangzhou Joyo Pharmatech Co., Ltd., Guangzhou (CN)
Filed by Guangzhou Joyo Pharmatech Co., Ltd., Guangdong (CN)
Filed on Mar. 3, 2025, as Appl. No. 19/069,098.
Application 19/069,098 is a continuation of application No. PCT/CN2023/122877, filed on Sep. 28, 2023.
Claims priority of application No. 202211213222.2 (CN), filed on Sep. 29, 2022; application No. 202310132699.6 (CN), filed on Feb. 17, 2023; application No. 202310371165.9 (CN), filed on Apr. 7, 2023; application No. 202310685748.9 (CN), filed on Jun. 9, 2023; and application No. 202310911632.2 (CN), filed on Jul. 24, 2023.
Prior Publication US 2025/0205245 A1, Jun. 26, 2025
Int. Cl. A61K 31/5383 (2006.01); A61K 31/5025 (2006.01); C07D 519/00 (2006.01)

CPC A61K 31/5383 (2013.01) [A61K 31/5025 (2013.01); C07D 519/00 (2013.01)]

30 Claims

1. A compound, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, selected from the group consisting of: