US 12,130,137 B2
Brillouin-octa-speckle multi-mode elastography system device
Xingdao He, Nanchang (CN); Jiulin Shi, Nanchang (CN); Yubao Zhang, Nanchang (CN); Zhongqi Hao, Nanchang (CN); Jin Xu, Nanchang (CN); and Gang Shi, Nanchang (CN)
Filed by Nanchang Hangkong University, Nanchang (CN)
Filed on Jan. 5, 2023, as Appl. No. 18/150,203.
Claims priority of application No. 202210894927.9 (CN), filed on Jul. 28, 2022.
Prior Publication US 2024/0035804 A1, Feb. 1, 2024
Int. Cl. G01J 3/44 (2006.01); G01B 9/02091 (2022.01)
CPC G01B 9/02091 (2013.01) 8 Claims
OG exemplary drawing
 
1. A Brillouin-optical coherence tomography angiography (OCTA)-speckle multi-mode elastography system device, comprising a Brillouin-OCTA sample scanning unit, a Brillouin scattering elastography system, an OCTA system, a speckle detection system, and a time sequence controller, wherein the Brillouin scattering elastography system and the OCTA system share the Brillouin-OCTA sample scanning unit, the Brillouin scattering elastography system comprises a Brillouin scattering signal excitation unit and a Brillouin signal acquisition unit, the OCTA system comprises an OCTA signal excitation unit and an OCTA signal acquisition unit, the speckle detection system comprises a speckle signal excitation unit and a speckle signal reception unit, and the Brillouin-OCTA sample scanning unit is composed of a dichroic mirror, a galvanometer set, a first optical shutter, and a scanning lens; wherein
the Brillouin-OCTA sample scanning unit is configured to generate an OCTA signal and a Brillouin signal of a sample synchronously;
the Brillouin signal excitation unit is configured to excite a Brillouin scattering signal;
the Brillouin signal acquisition unit is configured to acquire a Brillouin spectrum signal to generate blood vessel elasticity information;
the OCTA signal excitation unit is configured to excite a light scattering signal;
the OCTA signal acquisition unit is configured to acquire an OCTA signal to generate blood vessel distribution information;
the speckle signal excitation unit is configured to excite a wide-field speckle signal; and
the speckle signal reception unit is configured to acquire a speckle signal to generate blood flow relative velocity information.