US 12,129,489 B2
Yarn for cell culture scaffold, ply yarn comprising same and fabric comprising the same
In Yong Seo, Seoul (KR); Seon Ho Jang, Seoul (KR); Song Hee Koo, Gyeonggi-do (KR); Chan Kim, Gwangju (KR); and Seoung Hoon Lee, Gyeonggi-do (KR)
Assigned to AMOGREENTECH CO., LTD., Gimpso-si (KR)
Appl. No. 16/304,015
Filed by AMOGREENTECH CO., LTD., Gimpo-si (KR)
PCT Filed May 24, 2017, PCT No. PCT/KR2017/005426
§ 371(c)(1), (2) Date Nov. 21, 2018,
PCT Pub. No. WO2017/204564, PCT Pub. Date Nov. 30, 2017.
Claims priority of application No. 10-2016-0063854 (KR), filed on May 25, 2016.
Prior Publication US 2019/0203178 A1, Jul. 4, 2019
Int. Cl. D02G 3/02 (2006.01); A61L 27/16 (2006.01); A61L 27/38 (2006.01); A61L 27/44 (2006.01); C12N 5/00 (2006.01); C12N 5/077 (2010.01); D02G 1/02 (2006.01); D02G 3/26 (2006.01); D02G 3/44 (2006.01); D03D 15/00 (2021.01)
CPC C12N 5/0656 (2013.01) [A61L 27/16 (2013.01); A61L 27/38 (2013.01); A61L 27/3834 (2013.01); A61L 27/44 (2013.01); C12N 5/00 (2013.01); D02G 1/02 (2013.01); D02G 1/0206 (2013.01); D02G 1/0286 (2013.01); D02G 1/0293 (2013.01); D02G 3/02 (2013.01); D02G 3/26 (2013.01); D02G 3/448 (2013.01); D03D 15/00 (2013.01); C12N 2533/30 (2013.01); D10B 2201/02 (2013.01); D10B 2321/042 (2013.01); D10B 2331/02 (2013.01); D10B 2331/04 (2013.01); D10B 2509/00 (2013.01)] 6 Claims
OG exemplary drawing
 
1. A ply yarn for a cell culture scaffold, comprising:
a slitting yarn with a plurality of twists and fiber grooves, wherein the slitting yarn has a fineness of 0.01 to 30 denier and is a nanofiber web having a basis weight of 0.1 to 20 g/m2 in a three-dimensional network structure cut into multiple strands to have a width of 0.1 to 30 mm; and
the fiber grooves which are spaces formed between the twists and configured to provide three-dimensional growth spaces and migration paths for cell,
wherein the ply yarn comprises a plurality of macrotwists at a twist number of 100 to 5,000 twists/meter (T/m) and a twist angle of 20° to 60°, and macrofiber grooves between the plurality of macrotwists, wherein the ply yarn has a fineness of 0.5 to 1,000 denier and the macrofiber grooves are configured to provide three-dimensional growth spaces and migration paths for cells,
wherein the fiber grooves are formed continuously in the longitudinal direction of the ply yarn for a cell culture scaffold, and
wherein the ply yarn for a cell culture scaffold comprises microfiber grooves, which are spaces between the slitting yarn strands, formed on an outer surface of the ply yarn.